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Offering a breath of life for critically ill patients
A scientist by training, David Green (MBA 1991) is drawing upon his business acumen to lead a science fiction-style breakthrough: the creation of replacement body parts (specifically, the trachea) using a recipient’s stem cells.
Green is CEO of Massachusetts-based Harvard Apparatus Regenerative Technology, which manufactures the synthetic scaffolds and bioreactors used to seed the patient’s own bone marrow cells on the scaffold prior to transplant. The cells quickly grow a new trachea, which, because it is made from the patient’s own cells, is not rejected by the patient’s immune system. Patients suffering from diseases such as inoperable tracheal cancer, or those born without a trachea, have been granted a second chance.
As biotechnology and surgical expertise progress, Green foresees a future without waiting lists for organs such as the esophagus, lung, or heart. “I really think we’re at the beginning of a new era in medicine,” he says.
(Published April 2014)
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